To use the calabash gourd for food it is harvested while it is young, about 10 to 12 inches long, and used as a vegetable. Its flavor is similar to a summer squash and cucumber. The preferred way of preparing the calabash gourd is is to stir fry or boil it. It is a good source of vitamin A, vitamin C, some B vitamins, niacin, thiamine, riboflavin, calcium, potassium, iron, and a good source of fiber.
Some calabash gourds are used to create musical instruments such as the kora and balafon. They are also used to make women's rattles in Sierra Leone. Some very large calabash gourds are used as percussion intruments. In Nigeria, some motorcyclists wear calabash gourd helmets to get around the motorcycle helmet law.
* The calabash pipe is the choice of stage actors portraying Holmes in Sherlock Holmes plays.
* The design of the Soccer City stadium of South Africa took its inspiration from the shape of calabash. The 2010 FIFA World Cup was played there.