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Coenzyme Q 10 and conception

Coenzyme Q 10, more commonly known as CoQ 10, is another antioxidant. It may help with sperm motility and female egg development, especially if you're past age 35. Perhaps even if you're still in your 20s, too.

The other name for CoQ 10 is ubiquinone. It's metabolized in the body to the active form, ubiquinol. So you may see it listed as any of those names.

It's all over your body in every cell. Inside cells is the energy-producing machinery, which is run by the mitochondria, and they manufacture ATP from ubiquinol and NADH. That process is called "oxidative phosphorylation." The key word is "oxidative." ATP is the energy for the cells, whatever that cell does. If it's a cardiac muscle cell, then it needs to contract and relax to cause the heart to pump.

Likewise, if it's an immature egg cell, or oocyte, that cell needs energy. It needs a lot of energy, actually. Maturing from an immature cell to a fully mature egg is exhausting, and that's especially a problem for women over 35.

Not only is the role in energy production important, but CoQ 10 is also a free radical scavenger. Mitochondria are damaged by free radicals, and that leads to mutations in mitochondrial DNA, which is one reason why older eggs just don't fertilize or grow into quality embryos as easily as young eggs.
Ubiquinol levels decline naturally after about age 20 (so young!), and so if you're in your 30s, you could use some supplementation.

This isn't a quack supplement. It's commonly used in conjunction with medications for reducing cholesterol, a class of drugs called "statins." Statins block cholesterol synthesis, but they also non-selectively block synthesis of coenzyme Q 10. While studies have been contradictory as to whether it helps or not, some doctors recommend coenzyme Q 10 for patients taking statins.

Many more people take it even if they're not on a statin because it's an essential cofactor for any body function. I've read a few claim that it's our most important essential, meaning that we need to obtain it from food or supplements because our bodies don't make enough.

If you take it, look for ubiquinol, the active form. It's more expensive than Coenzyme Q 10. Both of its roles--energy production and antioxidant--are helpful for conception. Even for men because antioxidants can help sperm quality, too!




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