Connecticut
- 1728 First steel mill in America located in Simsbury
- 1809 First woman to receive a U.S. patent - Mary Kies
- 1810 First insurance company, ITT Hartford Group, Inc.
- 1858 First can opener
- 1868 First tape measure
- 1887 First torpedo boat - Stiletto
- 1895 First hamburger
- 1901 First automobile law was passed - The speed limit was set at 12 miles per hour.
- 1939 First helicopter
- 1948 First color television
- 1954 First nuclear powered submarine - Groton
Massachusetts
- 1621 First Thanksgiving Day celebrated - Plymouth
- 1634 First public park - Boston Common
- 1636 First college established - Harvard
- 1886 First town in the world to have electric street lights - Great Barrington
- 1891 First basketball game was played – Springfield
- 1895 First Volleyball game was played – Springfield
- 1897 First subway system – Boston
- First bible, dictionary and commercial valentine - printed in Worcester Ma
New Hampshire
- 1719 First potato planted in the United States – Londonderry
- 1787 First alarm clock
- 1833 First free public library in the United States - Peterborough
- 1908 First credit union
- 1923 First American in space - Alan Shepard
- 1938 First aerial passenger tramway - Franconia Notch
- First snowmobile
Rhode Island
- 1638 First Baptist Church in America
- 1652 First law against slavery
- First Afro-American regiment to fight for America against the British in the Battle of Rhode Island.
- First woman to establish a town in America – Portsmouth - Anne Hutchinson
- First street in the country to use gas-illuminated streetlights - Pelham Street in Newport
- 1774 First circus – Newport
- 1828 First shopping mall – Providence
- 1876 First Polo game
- 1887 First torpedo boat "Stiletto" was built in Bristol
- 1895 First auto race – Newport
Vermont
- 1785 First marble quarry - South Dorset
- 1802 First canal - Bellows Falls
- 1823 First African-American to receive a degree from an American College - Alexander Twilight
- 1846 First US Postage stamp is printed – Brattleboro
- 1934 First ski tow in the US - Woodstock.
- 1940 First Social Security benefits check - $22.54 to Ida May Fuller