The protagonist of the series is Jimmy Kudo, a 17-year-old high school student prodigy and detective. While working on a case, he was attacked by two members of a crime syndicate. They forced Jimmy to take an experimental poison that was supposed to kill him. After leaving him for dead, Jimmy ends up experiencing a rare side effect that the crime syndicate members were unaware of; Jimmy's body returned to that of his seven-year-old self. In order to hide his identity and investigate the syndicate, Jimmy takes on the pseudonym of Conan Edogawa.
As Conan, he moves in with his childhood friend, Rachel Moore and her father, Richard Moore (who is a former police officer that is now an incompetent private investigator). Rachel has been Jimmy's best friend since elementary school. Rachel and Jimmy have feelings for each other, but neither one has the courage to admit their feelings to the other. Rachel is talented in martial arts and is the captain of the school's karate team. After Conan moves in with her, Rachel has to spend her time looking after Conan and her father.
Conan enrolls at Teitan Elementary School and forms the Junior Detective League with three kids in his class: Amy, Mitch, and George. As Conan, he is still able to solve cases, usually by posing as Richard Moore with the help of special gadgets that are created by a scientist friend of Jimmy's family. The anime follows Conan as he tries to find out who poisoned him and their whereabouts.
Case Closed is a mystery anime done in a "Whodunit" style. Jimmy/Conan takes the time to explain the clues that led him to solve the mystery. While Jimmy may end up transforming into a seven-year-old boy, this series is not aimed at children that young. In the first episode, one of the mysteries presented is someone being murdered by being beheaded. A bloody knife is also shown on screen. With the subject matter and topics included in the series, as well as the storytelling used in the series, I would recommend Case Closed to anime viewers who are 13 or 14 years of age and older.
| Case Closed | 687 | 1996-ongoing | Kenji Kodama/Yasuichiro Yamamoto | TMS Entertainment | FUNimation Entertainment |
| Case Closed: The Time Bombed Skyscraper | N/A | 1997 | Kanetsugu Kodama | TMS Entertainment | FUNimation Entertainment |
| Case Closed: The Fourteenth Target | N/A | 1998 | Kanetsugu Kodama | TMS Entertainment | FUNimation Entertainment |
| Case Closed: The Last Wizard of the Century | N/A | 1999 | Kanetsugu Kodama | TMS Entertainment | FUNimation Entertainment |
| Conan vs Kid vs Yaiba – The Decisive Battle Over the Treasured Sword! | 1 | 2000 | ? | TMS Entertainment | N/A |
| Case Closed: Captured in Her Eyes | N/A | 2000 | Kenji Kodama | TMS Entertainment | FUNimation Entertainment |
| Case Closed: Countdown to Heaven | N/A | 2001 | Kanetsugu Kodama | TMS Entertainment | FUNimation Entertainment |
| 16 Suspects!? | 1 | 2002 | ? | TMS Entertainment | N/A |
| Case Closed: The Phantom of Baker Street | N/A | 2002 | Kanetsugu Kodama | TMS Entertainment | FUNimation Entertainment |
| Conan and Heiji and the Vanished Boy | 1 | 2003 | ? | TMS Entertainment | N/A |
| Case Closed: Crossroad in the Ancient Capital | N/A | 2003 | Kanetsugu Kodama | TMS Entertainment | N/A |
| Conan and Kid and the Crystal Mother | 1 | 2004 | ? | TMS Entertainment | N/A |
| Case Closed: Magician of the Silver Sky | N/A | 2004 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| The Target is Kogoro Mori!! The Detective Boys' Secret Investigation | 1 | 2005 | ? | TMS Entertainment | N/A |
| Case Closed: Strategy Above the Depths | N/A | 2005 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| Pursuit of the Vanished Diamond! Conan, Heiji vs Kid | 1 | 2006 | ? | TMS Entertainment | N/A |
| Case Closed: The Private Eyes' Requiem | N/A | 2006 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| A Written Challenge From Agasa! Agasa vs Conan & the Detective Boys | 1 | 2007 | ? | TMS Entertainment | N/A |
| Case Closed: Jolly Roger in the Deep Azure | N/A | 2007 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| Detective Conan Magic File | 4 | 2007 | ? | TMS Entertainment | N/A |
| High School Girl Detective Sonoko Suzuki’s Case Files | 1 | 2008 | ? | TMS Entertainment | N/A |
| Case Closed: Full Score of Fear | N/A | 2008 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| Detective Conan Magic File 2 | 1 | 2008 | ? | TMS Entertainment | N/A |
| Stranger in 10 Years | 1 | 2009 | ? | TMS Entertainment | N/A |
| Case Closed: The Raven Chaser | N/A | 2009 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| Detective Conan Magic File 3 | 1 | 2009 | ? | TMS Entertainment | N/A |
| Lupin the 3rd vs Detective Conan | 1 | 2009 | ? | TMS Entertainment | N/A |
| Kid in Trap Island | 1 | 2010 | ? | TMS Entertainment | N/A |
| Case Closed: The Lost Ship in the Sky | N/A | 2010 | Yasuichiro Yamamato | TMS Entertainment | N/A |
| Detective Conan Magic File 4 | 1 | 2010 | ? | TMS Entertainment | N/A |
| The Secret Order From London | 1 | 2011 | ? | TMS Entertainment | N/A |
| Case Closed: Quarter of Silence | N/A | 2011 | Yasuichiro Yamamato/Kobun Shizuno | TMS Entertainment | N/A |
| Detective Conan Magic File 2011 | 1 | 2011 | ? | TMS Entertainment | N/A |
| The Miracle of Excalibur | 1 | 2012 | ? | TMS Entertainment | N/A |
| Case Closed: The Eleventh Striker | N/A | 2012 | Kobun Shizuno | TMS Entertainment | N/A |
| Detective Conan Magic File 2012 | 1 | 2012 | ? | TMS Entertainment | N/A |
