logo
g Text Version
Beauty & Self
Books & Music
Career
Computers
Education
Family
Food & Wine
Health & Fitness
Hobbies & Crafts
Home & Garden
Money
News & Politics
Relationships
Religion & Spirituality
Sports
Travel & Culture
TV & Movies

dailyclick
Bored? Games!
Nutrition
Postcards
Take a Quiz
Rate My Photo

new
Bible Basics
Houseplants
Romance Movies
Creativity
Family Travel
Southwest USA
Irish Culture


dailyclick
All times in EST

Full Schedule
g
g Infertility Site

BellaOnline's Infertility Editor

g

Endometrioma and N-Acetyl Cysteine


Endometriomas are ovarian growths of endometriosis and they can cause considerable pain, if large they may need surgical removal and there is some concern about endometriomas reducing fertility. Conventional management may include use of the contraceptive pill, or other medication to reduce the presence of estrogen which tends to fuel endometrioma growth.

Endometriomas are thought to be sensitive to modulation via select antioxidants and an Italian study published in 2013 has discovered that N-acetyl cysteine (NAC) may be particularly a effective treatment strategy which does not interfere negatively with fertility.

The antioxidant NAC has been extensively studies in humans and is regarded as being extremely safe and non-toxic and prior studies in animals have demonstrated a remarkable ability to curb the growth and spread of endometriosis.

In this study, which was an observational cohort study, NAC treatment or no treatment was given to 92 Italian women who had ultrasound confirmed diagnoses of ovarian endometriosis. There were 47 women in the NAC-treated group and 45 in the untreated group. Treatment consisted of 600 mg of NAC three times a day on three consecutive days a week; although unusual, this three day on four day off schedule is thought to give optimal blood levels. All women were scheduled to undergo laparoscopic surgery 3 months later and their endometriomas measured at minimum 30 mm diameter.

After 3 months, in NAC-treated women the mean cyst diameter was reduced whereas in untreated women mean cyst diameter increased markedly (+6.6 mm). With
NAC treatment, more cysts tended to reduce in size and fewer cysts grew; twenty four of the NAC-treated women cancelled their surgeries due to either cyst reduction or resolution, pain reduction or pregnancy compared to only one woman in the untreated group. The researchers concluded that:

"Our results are better than those reported after hormonal treatments. Twenty-four NAC-treated patients—versus 1 within controls—cancelled scheduled laparoscopy due to cysts decrease/disappearance and/or relevant pain reduction (21 cases) or pregnancy ...."

"Eight pregnancies occurred in NAC-treated patients and 6 in untreated patients. We can conclude that NAC actually represents a simple effective treatment for endometriosis, without side effects, and a suitable approach for women desiring a pregnancy."

Pregnancies in NAC-treated women mostly occurred in the 2-12 month period following the study with an average of 6 months to conception. If you have an endometrioma and are trying to conceive you may want to ask your physician if NAC may be an option for you.

This article is for purely informational purposes and is not intended to diagnose or offer medical advice for which you should consult a suitably qualified physician.




Porpora M, Brunelli R, Costa G, eta l. A promise in the treatment of endometriosis: an observational cohort study on ovarian endometrionma reduction by N-acetylcysteine. Evid Based Complement Alternat Med. 2013. 240702.
http://dx.doi.org/10.1155/2013/240702.

Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Twitter Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Facebook Add Endometrioma+and+N%2DAcetyl+Cysteine+ to MySpace Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Del.icio.us Digg Endometrioma+and+N%2DAcetyl+Cysteine+ Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Yahoo My Web Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Google Bookmarks Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Stumbleupon Add Endometrioma+and+N%2DAcetyl+Cysteine+ to Reddit




RSS | Related Articles | Editor's Picks Articles | Top Ten Articles | Previous Features | Site Map


For FREE email updates, subscribe to the Infertility Newsletter


Past Issues


print
Printer Friendly
bookmark
Bookmark
tell friend
Tell a Friend
forum
Forum
email
Email Editor


Content copyright © 2014 by Hannah Calef. All rights reserved.
This content was written by Hannah Calef. If you wish to use this content in any manner, you need written permission. Contact Hannah Calef for details.

g


g features
Miscarriage And Poor Uterine Blood Flow

Important - Take Vitamin D With A Main Meal

PCOS? Check Your Homocysteine Levels

Archives | Site Map

forum
Forum
email
Contact

Past Issues
memberscenter


vote
Poetry
Daily
Weekly
Monthly
Less than Monthly



BellaOnline on Facebook
g


| About BellaOnline | Privacy Policy | Advertising | Become an Editor |
Website copyright © 2014 Minerva WebWorks LLC. All rights reserved.


BellaOnline Editor