New Research Getting Us Closer to Preventing Alzheimer’s
The goal of this research is to provide direction for preventative treatments to eliminate amyloid plaque-causing peptides in the brain during the earliest stages of AD when beta-amyloid peptides are already on the rise in the brain regions necessary for memory function.
The study explains that a possible reason for the early increase of beta-amyloid peptides is the inactivity of an enzyme that breaks them down, also known as an insulin-degrading enzyme (IDE).
A loss of IDE activity has been previously shown to occur in severe AD. The current results suggest that that the lack of IDE could raise levels of toxic beta-amyloid peptides even before AD is diagnosed. Mount Sinai researchers suggest that boosting IDE activity with drugs may even reverse beta-amyloid peptide accumulation. This presents a new therapeutic angle to preventing AD which afflicts 4.5 million Americans.
Debbie Mandel, MA is the author of Changing Habits: The Caregivers' Total Workout and Turn On Your Inner Light: Fitness for Body, Mind and Soul, a stress-reduction specialist, motivational speaker, a personal trainer and mind/body lecturer. She is the host of the weekly Turn On Your Inner Light Show on WGBB AM1240 in New York City , produces a weekly wellness newsletter, and has been featured on radio/ TV and print media. To learn more visit: www.turnonyourinnerlight.com
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