g Text Version
Beauty & Self
Books & Music
Food & Wine
Health & Fitness
Hobbies & Crafts
Home & Garden
News & Politics
Religion & Spirituality
Travel & Culture
TV & Movies

Bored? Games!
Take a Quiz
Rate My Photo

Family Travel
Southwest USA
Irish Culture
Home Finance
Comedy Movies
Romance Novels

All times in EST

Clairvoyance: 08:00 PM

Full Schedule
g Infertility Site

BellaOnline's Infertility Editor


Test Ovarian Antibodies Before IVF

Ovarian antibody testing (AOA) is controversial but new research is establishing a place for the AOA test prior to IVF to identify women at risk of IVF failure. Studies have shown that identifying such women can open up the possibility of corticosteroid treatment which suppresses antibody production before and during the IVF, proven to improve IVF success.

The AOA test establishes whether or not a woman has an autoimmune malfunction which has resulted in anti-ovarian antibodies attacking the ovaries in a similar fashion to the way in which the body attacks the joints in rheumatoid arthritis. An astute clinician may suspect ovarian antibodies if a woman has a history of poor IVF response, very low estradiol levels, and other auto immune factors but sometimes there are no hidden clues.

Infertility clinics vary greatly in the range tests that they offer women before commencing and IVF cycle. Some clinics offer very thorough tests and assess autoimmune factors before IVF while others seldom test immune factors - which may cause IVF failure and miscarriage - unless the patient has experienced 2-3 miscarriages.

This lack of testing can have very unfortunate consequences; some women experience multiple failed IVF cycles before discovering that auto-immune factors such as AOA may have been to blame. Had these factors been discovered - and treated - sooner maybe a different outcome may have been possible.

A 2010 study sought to establish whether AOA testing should have a higher profile in the batch of test offered to infertile women before IVF. Two groups of women undergoing IVF-ET were studied; group 1 were AOA positive who received corticosteroid therapy known to reduce antibody levels and enhance the outcome of IVF for such women. Group 2 did not have evidence of ovarian antibodies. A total of 570 infertile women were studied.

The researchers of the study concluded that:

"AOA testing could be included in the battery of tests investigating and treating infertility."

"Infertile women seeking assisted reproduction should have their serum tested for anti-ovarian antibodies prior to initiation of hormonal stimulation protocols. This would not only ensure efficacy of the IVF-ET but also save on the huge time and money invested on this protocol."

Even when AOA levels become undetectable subsequent to corticosteroid treatment, some women with a history of ovarian antibodies will still have a tendency to poor IVF response and a smaller number of oocytes at pick-up. Other women though will have their chances of succeeding significantly upped through AOA testing and the opportunity to pursue corticosteroid treatment. If you are about to pursue IVF this little piece of information may prove to be invaluable.

Can anti-ovarian antibody testing be useful in an IVF-ET clinic. Journal of Assisted Reproduction and Genetics. Eusebio S Pires, et al. Vol 28, number 1, 55-64, DOI:10.1007/s10815-010-9488-2

Add Test+Ovarian+Antibodies+Before+IVF to Twitter Add Test+Ovarian+Antibodies+Before+IVF to Facebook Add Test+Ovarian+Antibodies+Before+IVF to MySpace Add Test+Ovarian+Antibodies+Before+IVF to Del.icio.us Digg Test+Ovarian+Antibodies+Before+IVF Add Test+Ovarian+Antibodies+Before+IVF to Yahoo My Web Add Test+Ovarian+Antibodies+Before+IVF to Google Bookmarks Add Test+Ovarian+Antibodies+Before+IVF to Stumbleupon Add Test+Ovarian+Antibodies+Before+IVF to Reddit

Thyroid Antibody Treatment For IVF Success
Test Offers New Hope For IVF Success
Related Articles
Editor's Picks Articles
Top Ten Articles
Previous Features
Site Map

For FREE email updates, subscribe to the Infertility Newsletter

Past Issues

Printer Friendly
tell friend
Tell a Friend
Email Editor

Content copyright © 2014 by Hannah Calef. All rights reserved.
This content was written by Hannah Calef. If you wish to use this content in any manner, you need written permission. Contact Hannah Calef for details.


g features
Restore Key Fertility Minerals After The Pill

NAC May Perform As Well As Metformin In PCOS

PCOS? Could You Have Endometrial Polyps Too?

Archives | Site Map


Past Issues

Less than Monthly

BellaOnline on Facebook

| About BellaOnline | Privacy Policy | Advertising | Become an Editor |
Website copyright © 2014 Minerva WebWorks LLC. All rights reserved.

BellaOnline Editor